Full instructions are here:
The Mike Matas Blog: How to make a Life Poster:
Make a new iPhoto Album. Fill it with the 98 photos you want in your poster. Try to pick photos with lots of different colors. If you pick all indoor florescent light photos your poster is going to look like crap.
but I had never thought of using iPhoto to make a poster collage. Have to try it out. Maybe of a smattering of 2004 photos. Will post my results when I get to it.