These people are insane if they think I-35 is somehow holy. I've driven on it many times, and let me tell you, there are a lot of demons who traffic their hatred up and down the highway.
If you turn to the Bible -- Isaiah Chapter 35, Verse 8 -- you will see a passage that in part says, "A highway shall be there, and a road, and it shall be called the Highway of Holiness."
Now, is it possible that this "highway" mentioned in Chapter 35 is actually Interstate 35 that runs through six U.S. states, from southern Texas to northern Minnesota? Some Christians have faith that is indeed the case.
It was with that interesting belief in mind that we decided to head to Texas, the southernmost state in the I-35 corridor, to do a story about a prayer campaign called "Light the Highway."
[snip]
Jacobs also points out that perhaps there is a link between the area near this highway and tragedies that have happened in history, such as the bridge collapse on I-35 in Minneapolis last August and the assassination of JFK 44 years ago near I-35 in Dallas. That's why prayer certainly can't hurt, she adds.
Now, it's only fair to say most people, the religious and the non-religious alike, don't buy any of this, but none more than the owners of some of the adult businesses along I-35.
At an adult go-go club, the owner tells us he resents people trying to impose their will on others. And he says his club holds fundraisers, food drives and toy drives to help the community.
[From Tuchman: Hitting the road (literally) with some faithful - CNN.com]