Antibody Kills 91 percent of HIV Strains

Too early to return to the Studio 54 era1, but positive news nonetheless.

Rain slicked streets 1

In a significant step toward an AIDS vaccine, U.S. government scientists have discovered three powerful antibodies, the strongest of which neutralizes 91% of HIV strains, more than any AIDS antibody yet discovered.

The antibodies were discovered in the cells of a 60-year-old African-American gay man, known in the scientific literature as Donor 45, whose body made the antibodies naturally. Researchers screened 25 million of his cells to find 12 that produced the antibodies. Now the trick will be for scientists to develop a vaccine or other methods to make anyone’s body produce them.

That effort “will require work,” said Gary Nabel, director of the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases, who was a leader of the research. “We’re going to be at this for a while” before any benefit is seen in the clinic, he said.

The research was published Thursday in two papers in the online edition of the journal Science, 10 days before the opening of the large International AIDS Conference in Vienna, where prevention science is expected to take center stage.

(click to continue reading Antibody Kills 91% of HIV Strains – WSJ.com or here for non-subscribers)

 

Footnotes:
  1. shorthand for promiscuous, anonymous, unprotected sex, well, allegedly, I was too young to witness it myself, but I’ve heard tales []

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